Nox family NADPH oxidases: Molecular mechanisms of activation.
By R. Brandes, N. Weissmann, K. Schröder. Free Radical Biology & Medicine, 2014
650 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/106a0a1c090a34e2afb9a8a743cee15ccc16f067
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In Immunology
In Molecular Biology
- O. Maier
- Víctor M. Víctor
- Roman Fischer
- P. Venditti
- Tanea T Reed
- Colleen R. Reczek
- Navdeep S. Chandel
- S. Di Meo
In Physiology
Citations in the corpus
- Nrf2, the Master Regulator of Anti-Oxidative Responses (2017, background): “Because generation of reactive oxygen species (ROS) is an important characteristic of pro-inflammatory responses in phagocytes [38,39], Nrf2 is mainly an anti-inflammatory mediator, confining inflammatory responses [40].”
- ROS-dependent signal transduction (2014, background): “O2 is generated by the one-electron reduction of O2 through cytosolic NADPH oxidases (NOXs) and in mitochondrial electron transport chain (ETC) complexes I, II, and III (Figure 1) [5,6].”
- Role of ROS and RNS Sources in Physiological and Pathological Conditions (2016, background): “Cells can produce H 2 O 2 , O 2 ∙−, or NO∙ at physiological levels, but, in the case of diabetes, basal levels of ROS are elevated, and so these ROS and RNS are generally harmful.”
- Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF (2015, background): “Several NOX proteins are expressed in cells of the CNS including neurons, astrocytes, and microglia, with NOX2 as the predominant form in microglia and astrocytes [30, 31].”