Microsatellites within genes: structure, function, and evolution.

By You-Chun Li, A. Korol, T. Fahima, Eviatar Nevo. Molecular biology and evolution, 2004

1,134 citations recorded by the source corpus.

Subfields: Molecular Biology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/54b458f90f0f798b2a7b1900293d1965ff378293

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

Citations in the corpus

Microsatellites and their genomic distribution, evolution, function and applications : A review with special reference to fish genetics (2006, background): “A relatively low frequency of SSRs in coding regions could be explained by negative selection against frameshift mutations in the translated sequences (Metzgar et al., 2000; Li et al., 2004).”
Contribution of genetics and genomics to seagrass biology and conservation (2007, background): “Because simple repeat sequences serve as promoter binding sites, some microsatellite polymorphisms directly upstream of genes may have a direct functional significance (Li et al., 2004).”
Microsatellite markers: what they mean and why they are so useful (2016, background): “More and more publications have presented evidence that microsatellites play a role in relevant processes, such as the regulation of transcription and translation, organization of chromatin, genome size and the cell cycle (Nevo, 2001; Li et al., 2004; Gao et al., 2013).”
Map position and functional allelic diversity of Md-Exp7, a new putative expansin gene associated with fruit softening in apple (Malus × domestica Borkh.) and pear (Pyrus communis) (2008, background): “They may interfere with transcription activity, influencing the interaction with regulatory proteins by changing the distance between transcriptional factors binding sites (Li et al. 2004).”
Development, characterization and utilization of microsatellite markers in pigeonpea (2007, background): “2001) and are characterized with more repeat numbers (Li et al. 2004) making them the best source of highly polymorphic SSR markers.”
Genic microsatellite markers in plants: features and applications. (2005, background): “The presence of SSRs in the transcripts of genes suggests that they might have a role in gene expression or function; however, it remains to be seen whether any unusual phenotypic variation might be associated with the length of SSRs in coding regions, as was reported for several diseases in humans ”
Identifying a Carotenoid Cleavage Dioxygenase (ccd4) Gene Controlling Yellow/White Fruit Flesh Color of Peach (2013, background): “Slip-strand mispairing errors are corrected by mismatch repair (MMR) systems, thus SSR stability depends upon a balance between the DNA slippage and the repair effectiveness; when the MMR system is altered, SSR instability increases (Li et al. 2004).”
25 Oxytocin and Vasopressin: Genetics and Behavioral Implications (2006, background): “These microsatellite sequences are repetitive, unstable (Li et al., 2004), and can modulate gene expression levels and regional distribution (Hammock and Young, 2002; Hammock et al.”
Intragenic tandem repeats generate functional variability (2005, background): “In humans, expansion of intragenic triplet repeats is associated with various diseases, including Huntington chorea and fragile X syndrom”
Microsatellite markers: an overview of the recent progress in plants (2011, background): “Majority of intronic SSRs are monomeric and/or dimers in different taxonomic groups (Li et al. 2004).”
Domestication evolution, genetics and genomics in wheat (2011, background): “The relationship between genomic and epigenomic diversities (Kashkush et al. 2002; Levy and Feldman 2004; Kashkush 2007) could be highlighted by deciphering the regulatory function of noncoding genomes on genic components (Li et al. 2002, 2003, 2004).”
The emerging role of genetic diversity for ecosystem functioning: Estuarine macrophytes as models (2006, background): “Recently, abundant microsatellites have also been discovered in the immediate vicinity of expressed genes (gene-linked or type-1 microsatellites), prompting the question whether the general assumption of their selective neutrality is still tenable (Li et al. 2004).”
Genetic Diversity of Twelve Switchgrass Populations Using Molecular and Morphological Markers (2010, background): “They have been shown to have roles in gene expression, regulation of DNA recombination, transcription and translation, as well as putative roles in providing an adaptive advantage [6, 27, 48].”