Research report Nucleus accumbens dopamine and work requirements on interval schedules

By B. Carlson, A. Wisniecki, John Salamone. 2002

131 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/53b425b1af3c2709323e1a36dec2be08504f6634

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Citations in the corpus

Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits (2007, background): “Although it is generally observed that there is recovery of behavioral function after DA depletions (Zigmond et al. 1984; Salamone et al. 1990; Correa et al. 2002), this effect also appears to depend upon the ratio requirement; although responding on FR4 or FR5 schedules exhibited rapid recovery (i.”
Reconsidering Anhedonia in Depression: Lessons from Translational Neuroscience (2010, methodology): “…it was demonstrated that while control rats prefer the HC/HR option, rats with NAcc DA lesions or blockade of striatal D2 receptors show increased preference for the LC/LR option (Correa et al., 2002; Cousins et al., 1996; Cousins and Salamone, 1994; Denk et al., 2005; Salamone et al., 2007).”
The mysterious motivational functions of mesolimbic dopamine. (2012, unknown): “…reinforcement that have ratio requirements attached to time interval requirements indicate that accumbens DA depletions make animals more sensitive to added ratio requirements but do not make animals sensitive to time interval requirements from 30–120 s (Correa et al., 2002; Mingote et al., 2005 ).”
The Neurobiology of Anhedonia and Other Reward-Related Deficits (2011, background): “Similar dopamine lesions also decreased responding for rewards requiring five, but not one, successive responses [63], indicating that NAc dopamine is necessary to elicit responding for rewards when the required effort is increased (reviewed in [64]).”
Worth the ‘EEfRT’? The Effort Expenditure for Rewards Task as an Objective Measure of Motivation and Anhedonia (2009, background): “In contrast, ventral striatal (nucleus accumbens) DA depletion results in a reduced willingness to expend effort in order to obtain rewards [30,31,32].”