Neuropathology of Cognitively Normal Elderly

By D. Knopman, Joseph E. Parisi, A. Salviati, M. Floriach-Robert, Brad Boeve, R. Ivnik, Glenn E. Smith, D. Dickson, Keith A. Johnson, Lindsay E. Petersen and 3 more. Journal of Neuropathology and Experimental Neurology, 2003

676 citations recorded by the source corpus.

Subfields: Neurology, Physiology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/535bb8fbe023fef3805d828bc58dcdca3cc2ebf9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

In Physiology

In Psychiatry and Mental health

Citations in the corpus

Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease (2017, methodology): “Consistent with neuropathological data, more than 40% of MCI patients included in our study were categorized as Braak ROIbased stage III/IV (Knopman et al., 2003).”
Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade (2010, neutral): “…AD is a hypothesis rather than a statement of fact, because some of these individuals will die without ever expressing clinical symptoms.3– 5 The hypothetical assumption is that an asymptomatic individual with pathological changes that are indicative of AD would ultimately have become…”
Defining imaging biomarker cut points for brain aging and Alzheimer's disease (2017, neutral): “Similarly, around 30% of clinically normal elderly individuals have AD at autopsy [21] or have biomarker evidence of amyloidosis [22– 24], and therefore, a clinically defined “unaffected” non-AD control group also has significant inherent error [17].”
Deciphering the molecular basis of memory failure in Alzheimer's disease. (2004, background): “Importantly, are detected in a significant proportion of the nondein a rare case of the translocation form of Down's synmented elderly (Knopman et al., 2003).”
The overlap between vascular disease and Alzheimer’s disease - lessons from pathology (2014, background): “, small or large cerebral infarcts, lacunes, and WMLs, in up to 10% [10,165-167].”
Religious Orders Study and Rush Memory and Aging Project (2018, neutral): “These data complement data from other clinical-pathologic stud-iesillustratingthatADpathologyispresentinpersonswithoutdementia[351–353].”
Neuropathological alterations in Alzheimer disease. (2011, background): “Longitudinal prospective clinicopathological studies in nondemented elderly people have revealed that up to 45% of nondemented elderly would meet the NIA-RI criteria for AD had they been demented, usually the intermediate likelihood category of these criteria, and rarely the high likelihood category”