CRISPR — a widespread system that provides acquired resistance against phages in bacteria and archaea

By Rotem Sorek, Victor Kunin, Philip Hugenholtz. Nature Reviews Microbiology, 2008

848 citations recorded by the source corpus.

Subfields: Ecology, Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/53068e84d61969ba0c02d51c9464eda00a6cff3f

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Citations in the corpus

RASTtk: A modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes (2015, background): “Because of their importance in horizontal gene transfer and in biotechnology 26,27 , we have added a script to the RASTtk pipeline that finds CRISPR elements.”
Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches. (2011, background): “phage (Sorek et al., 2008).”
Regulatory RNAs in Bacteria (2009, background): “Adjacent to the CRISPR DNA array are several CRISPR-associated (CAS) genes (reviewed in Sorek et al., 2008).”
New CRISPR-Cas systems from uncultivated microbes (2016, methodology): “Metagenomic samples from three different sites were analyzed: (1) Acid mine drainage (AMD) samples collected between 2006 and 2010 from the Richmond Mine, Iron Mountain, California36,37 (2) Groundwater and sediment samples collected between 2007 and 2013 from the Rifle Integrated Field Research (IFR”
CRISPR/Cas system and its role in phage-bacteria interactions. (2010, background): “Each program has its own merits and shortcomings already discussed elsewhere (10, 81).”
The genomic basis of trophic strategy in marine bacteria (2009, background): “CRISPRs are clusters of repeats interspersed with short phage-derived sequences that have been proposed to confer hosts with resistance to phages (19), and their abundance is therefore expected to correlate with resistance to phage infection.”
Short motif sequences determine the targets of the prokaryotic CRISPR defence system. (2009, methodology): “For detailed descriptions of the CRISPR systems see Lillestøl et al. (2006) and Sorek et al. (2008).”
Explaining microbial population genomics through phage predation (2009, background): “html">Supplementary information S2 (table)) that are involved in phage interferenc”
Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world (2008, background): “Recently, a novel and highly unusual class of defense systems has been shown to exist in approximately half of bacteria and archaea whose genomes have been sequenced (230).”