Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

By S. Sharif, G. Arreaza, P. Zucker, Q. Mi, J. Sondhi, O. Naidenko, M. Kronenberg, Y. Koezuka, T. Delovitch, J. Gombert and 10 more. Nature Medicine, 2001

652 citations recorded by the source corpus.

Subfields: Genetics, Immunology

View Paper: https://www.semanticscholar.org/paper/52884b4c5552cccaf9b5d774badc89b9996d62c9

How researchers see this paper

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In Immunology

1. A. Bendelac
2. L. Teyton
3. R. Ross
4. P. Savage
5. C. Stanton
6. M. Kronenberg

Citations in the corpus

• Marine Bioactives as Functional Food Ingredients: Potential to Reduce the Incidence of Chronic Diseases (2011, background): “Compound Source Experimental model Effect/Mechanism of action Reference α-galactosylceramide Agelas mauritianus sponge Non-obese diabetic mice Suppression of IFN-γ, increase of serum Ig E levels, and promotion of islet autoantigen specific Th2 cells Suppression of T- and B-cell autoimmunity to islet”
• The biology of NKT cells. (2007, background): “Likewise, the suppression of diabetes by αGalCer multi-injection regimens could be the mere consequence of massive cytokine release (220, 221).”