The art and design of genetic screens: Drosophila melanogaster
By Daniel St Johnston. Nature reviews genetics, 2002
685 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/51e053056a5f67b43e4ee0fa24a7995fc735077c
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cellular and Molecular Neuroscience
- David P. Bartel
- Matthew W. Hahn
- Hugo J. Bellen
- K. Venken
- Julie H. Simpson
- David J. Anderson
- Ralph Adolphs
In Molecular Biology
- David P. Bartel
- Manolis Kellis
- Alexander Stark
- David Haussler
- Eric C. Lai
- J. Brennecke
- Gregory J. Hannon
- J. Ruby
Citations in the corpus
- Genetic manipulation of genes and cells in the nervous system of the fruit fly (2011, background): “7b. Transposon Mutagenesis Forward genetic screens based on transposon mutagenesis to identify new loci affecting neuronal features have so far been based on P elements (St Johnston, 2002) and piggyBac (Schuldiner et al., 2008).”
- Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures (2007, background): “Moreover, the fruit-fly benefits from extensive experimental resources 26–28 , which enable novel functional elements to be systematically tested and used in the evaluation of genetic screens 29,30 .”
- A Transgenic Drosophila Model Demonstrates That the Helicobacter pylori CagA Protein Functions as a Eukaryotic Gab Adaptor (2008, background): “Finally, Drosophila are amenable to forward genetic approaches that will facilitate the discovery of host factors required for CagA function in eukaryotic cells [22].”
- Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification (2005, background): “Studies in model organisms such as Drosophila have demonstrated the complex interplay of signaling molecules that underlie developmental events associated with the embryonic maturation of tissues and cell types (St Johnston, 2002).”
- Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease (2013, background): “In Drosophila, chemical and insertional mutagenesis are powerful and widely utilized methods for disrupting gene function (St Johnston 2002; Venken and Bellen 2005).”