Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress.
By R. Motterlini, R. Foresti, Rekha Bassi, Colin J. Green. Free Radical Biology & Medicine, 2000
888 citations recorded by the source corpus.
Subfields: Molecular Biology, Molecular Medicine, Pharmacology
View Paper: https://www.semanticscholar.org/paper/51d3db868876dad72c8393814147a4b5a731770e
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Citations in the corpus
- Effects of Dietary Supplementation with Turmeric Rhizome Extract on Growth Performance, Carcass Characteristics, Antioxidant Capability, and Meat Quality of Wenchang Broiler Chickens (2015, background): “It has the ability to inhibit lipid peroxidation and scavenge the superoxide anion and hydroxyl radicals (Motterlini et al., 2000).”
- Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders (2010, neutral): “…of the parallels between the effects mediated by increased RNS and ROS is the ability of cells to respond to these two types of stress, and depending on the severity of the nitrosative = oxidative insult, this response may result in adaptation and resistance to toxicity (108, 179, 281, 292, 317).”
- Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment (2011, background): “Increased heme oxygenase activity also appears to play an important role in curcumin-mediated cytoprotection against oxidative stress and NO-induced toxicity or apoptosis [78].”
- Curcumin: Preventive and Therapeutic Properties in Laboratory Studies and Clinical Trials (2008, neutral): “Increased heme oxygenase activity also appears to play an important role in curcumin-mediated cytoprotection against oxidative stress and nitric oxide–induced toxicity or apoptosis (177).”
- Pharmacological and Clinical Aspects of Heme Oxygenase (2008, neutral): “Increased HO activity is an important component in curcumin-mediated cytoprotection against oxidative stress (Motterlini et al., 2000).”
- Multiple biological activities of curcumin: a short review. (2006, background): “Vascular endothelial cells treated with curcumin prevented oxidant mediated injury by increased heme oxygenase production (Motterlini et al., 2000).”
- Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications (2005, background): “, 1981), radiation, ultraviolet, hydrogen peroxide, hypoxia, endotoxin, growth factors [platelet-derived growth factor (PDGF) and transforming growth factor (TGF- )], various electrophiles, okadaic acid, methylglyoxal (Wu, 2005), curcumin (Motterlini et al., 2000), oxidative stress (Nath et al.”
- Biological Properties of Curcumin-Cellular and Molecular Mechanisms of Action (2004, background): “Another mechanism by which curcumin protects against oxidative stress in endothelial cells is by the induction of heme oxygenase-1 ( Motterlini et al, 2000 ).”