Robust 4C-seq data analysis to screen for regulatory DNA interactions
By Harmen van de Werken, G. Landan, Sjoerd J. B. Holwerda, Michael Hoichman, P. Klous, Ran Chachik, Erik Splinter, Christian Valdes-Quezada, Y. Öz, Britta A. M. Bouwman and 4 more. Nature Methods, 2012
400 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/50eff902e17cd48965f0b52be2d31b36fa5c3ab9
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Richard A. Young
- Denes Hnisz
- W. de Laat
- James E. Bradner
- B. Abraham
- Amos Tanay
- R. Jaenisch
- N. Hannett
Citations in the corpus
- A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia. (2014, methodology): “To test whether the CTS harbored elements physically interacting with the EVI1 promoter, we performed high-resolution chromosome conformation capture sequencing (4C-seq) experiments (van de Werken et al., 2012).”
- YY1 Is a Structural Regulator of Enhancer-Promoter Loops (2017, positive): “A modified version of 4C-seq (van de Werken et al., 2012a, 2012b) was developed.”
- CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data (2015, neutral): “3), as in other 3C/Hi-C-like methods [6-10, 12, 13, 19, 20].”
- Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture (2015, methodology): “Mouse primers were designed according to the genome-wide 4C-seq primer database from (van de Werken et al., 2012).”