OXA-48-like carbapenemases: the phantom menace.

By L. Poirel, A. Potron, P. Nordmann. Journal of Antimicrobial Chemotherapy, 2012

901 citations recorded by the source corpus.

Subfields: Endocrinology, Molecular Medicine, Pollution

View Paper: https://www.semanticscholar.org/paper/5075f9a13376b31573835f85cfe8bd975b5a7621

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology

1. P. Nordmann
2. L. Poirel
3. F. Codjoe
4. E. Donkor
5. K. Bush
6. J. Pitout
7. P. Bradford
8. G. Meletis

In Molecular Medicine

1. P. Nordmann
2. L. Poirel
3. K. Bush
4. P. Bradford
5. J. Pitout
6. F. Codjoe
7. E. Donkor
8. G. Meletis

In Pollution

1. F. Codjoe
2. E. Donkor
3. P. Nordmann
4. L. Poirel
5. K. Bush
6. Young Bae Kim
7. Jung Hun Lee
8. Chang-Ro Lee

Citations in the corpus

• Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance (2015, background): “, Morocco, Tunisia, Spain, Belgium) and shows a wide range of susceptibility profiles (25).”
• Carbapenem resistance: overview of the problem and future perspectives (2016, background): “The most effective carbapenemases, in terms of carbapenem hydrolysis and geographical spread, are KPC, VIM, IMP, NDM and OXA-48 types [Poirel et al. 2012].”
• Carbapenem Resistance: A Review (2017, background): “Others in the same category, often considered commensals, typically carry chromosomal metallo-β-lactamase enzymes, which are not transferrable, from the groups which had a serine-based hydrolytic mechanism of action [37,38].”
• Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer (2016, background): “The OXA-48-type carbapenem-hydrolyzing β-lactamase genes, which are increasingly reported in enterobacterial species worldwide, were also found to originate from the chromosomes of waterborne, environmental Shewanella species (Poirel et al., 2012).”
• Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods (2016, background): “(1) Turkey; (2) Morocco; (3) Tunisia; (4) Libya; (5) Egypt; (6) India; (7) Argentina; (8) Spain; (9) France; (10) Germany; (11) Switzerland; (12) Belgium; (13) Netherlands; (14) UK; (15) Italy; (16) Israel; (17) Saudi Arabia; (18) Kuwait; (19) Lebanon; (20) Japan; (21) Canada; (22) USA; (23) Ireland”
• The global epidemiology of carbapenemase-producing Enterobacteriaceae (2017, result): “In contrast, they are relatively commonly found in Europe, especially in Mediterranean countries.(20) The first reported OXA-48-producing Enterobacteriaceae”
• Epidemiology of β-Lactamase-Producing Pathogens (2020, background): “values, with many imipenem MICs of 2 g/ml (241, 242).”
• The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide. (2014, background): “by a single amino acid substitution together with a four amino-acid deletion [95,136].”
• The Epidemiology of Carbapenem-Resistant Enterobacteriaceae: The Impact and Evolution of a Global Menace (2017, background): “spectrum cephalosporins; however, strains may express multiple ESBLs, rendering them resistant to all β-lactams [12].”
• The Role of Epidemic Resistance Plasmids and International High-Risk Clones in the Spread of Multidrug-Resistant Enterobacteriaceae (2015, background): “This suggests that certain ancestral plasmids are particularly well suited to Enterobacteriaceae such as K. pneumoniae and are good candidates for sustaining the presence of blaKPC through multiple independent insertion and transposition events.”