Novel Type V Staphylococcal Cassette Chromosome mec Driven by a Novel Cassette Chromosome Recombinase, ccrC

By Teruyo Ito, X. Ma, Fumihiko Takeuchi, K. Okuma, H. Yuzawa, K. Hiramatsu. Antimicrobial Agents and Chemotherapy, 2004

760 citations recorded by the source corpus.

Subfields: Genetics, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0cc0ab5dc44af42ab19c377a6a6abc076a05502b

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Citations in the corpus

Classification of Staphylococcal Cassette Chromosome mec (SCCmec): Guidelines for Reporting Novel SCCmec Elements (2009, methodology): “Red arrowheads indicate the ISS of SCC that comprise DR sequences. a ccr genes in the gene complex are indicated in parentheses. b ccrA4B4 genes found in type VIII SCCmec were nearly identical to those in the S. epidermidis SCC-CI element and showed nucleotide identities of 89.6% and 94.5% to those ”
The molecular evolution of methicillin-resistant Staphylococcus aureus. (2007, background): “Coombs GW, Nimmo GR, Bell JM et al. Genetic diversity among community methicillin-resistant Staphylococcus aureus strains causing outpatient infections in Australia.”
Community-Associated Methicillin-Resistant Staphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic (2010, background): “aureus strains and, therefore, are more commonly associated with MDR phenotypes (392, 430).”
Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology (2018, background): “After finding several strains with untypeable SCCmec, sequencing of the region in strain WIS was done and identified a novel SCCmec cassette containing a class C2 mec gene complex and a type 5 ccr gene complex (183, 184).”
Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. (2005, background): “Types I-V and additional SCCmec elements have been described elsewhere; however, community-onset MRSA (CO-MRSA) infections have mostly been associated with type IV [3, 11-15].”
The evolution of Staphylococcus aureus. (2008, background): “Three years later, in 1985, a MRSA strain (85/2082) harboring SCCmec type III was found in New Zealand.”
Novel Multiplex PCR Assay for Characterization and Concomitant Subtyping of Staphylococcal Cassette Chromosome mec Types I to V in Methicillin-Resistant Staphylococcus aureus (2005, methodology): “The only previously described multiplex PCR assay for SCCmec typing (24) is more difficult to interpret and is limited in its ability to detect SCCmec subtypes IVa, b, c, and d plus the newly described type V, these groups being implicated in currently emerging community MRSA outbreaks (12, 31).”
Genomic islands: tools of bacterial horizontal gene transfer and evolution (2008, background): “GEI SCCmec is interesting in a sense that it does not contain phage-related and tra genes or transposases and is transferred between bacteria with the help of two site-specific recombinases that catalyze its chromosomal excision and reintegration (Ito et al., 2004; Noto & Archer, 2006).”
Combination of Multiplex PCRs for Staphylococcal Cassette Chromosome mec Type Assignment: Rapid Identification System for mec, ccr, and Major Differences in Junkyard Regions (2006, background): “ccr types 1 to 4 carry the ccrA and ccrB genes, which share approximately 80% identity with each other, and the type 5 ccr carries the ccrC gene (10, 11, 17, 19).”