Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium.

By S. Bratu, D. Landman, Robin Haag, R. Recco, A. Eramo, Maqsood Alam, J. Quale. Archives of Internal Medicine, 2005

626 citations recorded by the source corpus.

Subfields: Critical Care and Intensive Care Medicine, Endocrinology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/50295be21828d8a7148e21a2d8a5c77907772ef2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Critical Care and Intensive Care Medicine

1. Emily R. M. Sydnor
2. Trish Perl
3. Evelina Tacconelli
4. D. Livermore
5. F. Tenover

In Endocrinology

1. K. Bush
2. Trish Perl
3. A. Queenan
4. G. Jacoby
5. P. Nordmann
6. L. Poirel

In Molecular Medicine

1. K. Bush
2. D. Livermore
3. Trish Perl
4. A. Queenan
5. F. Tenover
6. G. Jacoby
7. P. Nordmann
8. L. Poirel

Citations in the corpus

• ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients. (2014, background): “The majority (86%) of these patients were not identified by routine clinical cultures [145].”
• Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. (2011, background): “Although CRE have primarily been recognized in health care settings [3, 8], Enterobacteriaceae are common causes of both health care and community infections, raising the possibility of spread of CRE into the community.”
• Carbapenemases: the Versatile β-Lactamases (2007, background): “which results in high mortality rates (15).”
• Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance. (2011, background): “Endimiani A, Carias LL, Hujer AM et al. (2008) Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.”
• Hospital Epidemiology and Infection Control in Acute-Care Settings (2011, background): “The first carbapenemase-producing Klebsiella species were reported in the late 1990s (360); however, these organisms did not gain notoriety until outbreaks of KPC-producing Klebsiella species were reported around the world (34, 36, 180, 306, 332).”
• Updated Functional Classification of β-Lactamases (2009, background): “The KPC carbapenemases in particular have recently been associated with major outbreaks of multidrug-resistant Gram-negative infections in hospitals, including those in the New York City metropolitan area (10, 12, 70) and in Israel (32), with their spread now becoming worldwide (43, 63, 68).”
• Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions (2012, background): “Animals were infected with three VIM-1-positive isolates (with imipenem MICs of 2, 4, and 32 g/ml) and a susceptible clinical isolate (with an imipenem MIC of 0.125 g/ml) not producing any -lactamase with broad-spectrum activity.”
• Predictors of mortality in bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae: importance of combination therapy. (2012, background): “eastern United States, Israel, and Greece, where they are now considered endemic [1-2,4-6].”
• Combating antimicrobial resistance: policy recommendations to save lives. (2011, positive): “carbapenemase-producing Klebsiella pneumoniae [30, 31], and”