Hippocampus Leads Ventral Striatum in Replay of Place-Reward Information

By Carien Lansink, P. M. Goltstein, J. Lankelma, Bruce L. McNaughton, Cyriel M. A. Pennartz. 2009

413 citations recorded by the source corpus.

While the brain is asleep, the hippocampus plays first fiddle in the orchestra of memory; spatial information is reactivated in the hippocampus shortly in advance of emotional memory traces in the vental striatum.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

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Citations in the corpus

About sleep's role in memory. (2013, neutral): “Concurrent replay patterns in the hippocampus occurred shortly before striatal reactivations (699, 700) and, in contrast to hippocampal replay, reactivation in the striatum did not decay during the 40 min recording period (914).”
Replay Comes of Age. (2017, background): “Indeed, both nucleus accumbens (Lansink et al. 2009, Pennartz et al. 2004) and prefrontal cortex ( Jadhav et al. 2016) exhibit activity that is temporally coordinated with hippocampal replay, as is the activity of dopamine neurons in the ventral tegmental area (Gomperts et al. 2015), in line with…”
Slow-Wave Sleep-Imposed Replay Modulates Both Strength and Precision of Memory (2014, background): “Such replay is hypothesized to be critical for reinforcing synaptic changes induced by the initial learning (Lansink et al., 2009), transference of information across brain regions (Ji and Wilson, 2007), and homeostatic resetting of synaptic strength (Tononi, 2009).”
A dedicated population for reward coding in the hippocampus (2018, neutral): “Previous studies employing a variety of navigation paradigms have examined the density of spatial fields near a goal or reward (Fyhn et al., 2002; Lansink et al., 2009; van derMeer et al., 2010; Dupret et al., 2010; Danielson et al., 2016; Zaremba et al., 2017), and in some cases, but not all, an ex”
Prioritized memory access explains planning and hippocampal replay (2017, background): “…likely cortico-striatal synapses), and the fuller neural processes of replay presumably involve coordinated evoked activity throughout the brain, especially including value prediction and learning in the mesolimbic and nigrostriatal reward networks (Gomperts et al., 2015; Lansink et al., 2009).”
What Learning Systems do Intelligent Agents Need? Complementary Learning Systems Theory Updated. (2016, positive): “Furthermore, a recent study observed coordinated reactivation of hippocampal and ventral striatal neurons during slow-wave sleep (SWS), with location-speci ﬁ c hippocampal replay preceding activity in reward-sensitive striatal neurons [66].”
Sequence Learning and the Role of the Hippocampus in Rodent Navigation (2012, positive): “Moreover, ventral striatum neurons exhibit a close connection to fine-timescale dynamics in the hippocampal representation of state, specifically theta phase precession [25 ], forward sweeps [23 ], and replay [22,27,28], which are discussed in the following sections.”
The reorganization and reactivation of hippocampal maps predict spatial memory performance (2010, positive): “Further support for a role in system-level memory consolidation comes from studies reporting coordinated reactivation across brain regions: reward-related firing patterns reactivate together in the striatum and the hippocampus 45 .”