An evolving hierarchical family classification for glycosyltransferases.
By Pedro M. Coutinho, E. Deleury, G. Davies, Bernard Henrissat. 2003
1,182 citations recorded by the source corpus.
Subfields: Biotechnology, Molecular Biology, Organic Chemistry
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Biotechnology
In Molecular Biology
In Organic Chemistry
Citations in the corpus
- Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases (2003, background): “Sequence lignments revealed two highly conserved regions within the catalytic domain, the second one including the catalytic center (Henrissat, 1991; Coutinho et al., 2003; see also Fig.”
- Crystal structure of mammalian α1,6-fucosyltransferase, FUT8 (2007, background): “On the other hand, GT-B enzymes have folds consisting of two similar Rossmann folds (Couinho et al. 2003; Qasba et al. 2005).”
- Dystroglycan Function Requires Xylosyl- and Glucuronyltransferase Activities of LARGE (2012, methodology): “Given that one of the two domains of LARGE belongs to glycosyltransferase family 8 (GT8), whose members generate products with an a-linked glycosidic bond (13), we tested a-D-xyloside for the ability to inhibit functional modification of a-DG.”
- Chitin Metabolism in Insects (2012, methodology): “Modular structure of chitin synthases CHSs are members of family GT2 of the glycosyltransferases (Coutinho et al., 2003), which generally utilize a mechanism where inversion of the anomeric configuration of the sugar donor occurs.”
- Glycosylation with activated sugars using glycosyltransferases and transglycosidases (2006, methodology): “1994), and GT-B-fold family as described for the phage T4 b-glucosyltransferase and the catalytic core of glycogen phosphorylase (Charnock & Davies 1999; Bourne & Henrissat 2001; Coutinho et al. 2003).”
- Structures and mechanisms of glycosyltransferases. (2006, methodology): “This sequence-based classification is assumed to integrate both structural and mechanistic features within each family (Coutinho et al., 2003).”
- Pectin structure and biosynthesis. (2008, neutral): “org) GT-8 family [32 ,53].”