Fibrin: A Versatile Scaffold for Tissue Engineering Applications

By Tamer A E Ahmed, E. Dare, M. Hincke. Tissue engineering. Part B, Reviews, 2008

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Current development of biodegradable polymeric materials for biomedical applications (2018, background): “51 One of the first developed fibrin-based products was fibrin glue (fibrin sealant).”
Laser assisted bioprinting of engineered tissue with high cell density and microscale organization. (2010, background): “Fibrin is a versatile biopolymer, which presents potential for tissue engineering applications [21].”
Bone tissue engineering: A review in bone biomimetics and drug delivery strategies (2009, background): “Proteins delivered to the site of an injury via blood, such as fibrin and fibrinogen, have also been investigated as scaffold materials for their hemostatic and cell-binding capacity.(157) Several other naturally derived polymers such as silkworm silk fibers exhibit comparable biocompatibility in vi”
Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning (2018, background): “While it has been used for in vitro cultures, including angiogenesis studies, biomechanical studies and mesenchymal stem cell culture, its high susceptibility to protease-mediated degradation limits its use in long-term cultures (Ahmed et al., 2008; Anitua et al., 2013; Kural and Billiar, 2013; Brow”