Identification of a Heteromeric Complex That Promotes DNA Replication Origin Firing in Human Cells

By Dominik Boos, M. Yekezare, J. Diffley. 2013

98 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. A. Kumagai
2. W. G. Dunphy
3. Johannes C. Walter

In Molecular Biology

1. A. Kumagai
2. W. G. Dunphy
3. Johannes C. Walter
4. Masato T. Kanemaki
5. Sachiko Muramatsu

In Oncology

1. A. Kumagai
2. Masato T. Kanemaki
3. W. G. Dunphy

Citations in the corpus

• In silico protein interaction screening uncovers DONSON’s role in replication initiation (2023, background): “Indeed,knock-downofMTBPorTRESLIN, which act upstream of DONSON, reduces origin firing and increases fork rates, but unlike DONSON, does not cause fork asymmetry ( 11 , 12 , 47 ).”
• MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication (2017, methodology): “For these assays, we utilized a structure called H45 which contains tandem G4 structures from human telomeric DNA (Bugaut and Alberti, 2015).”