Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia

By Serkan Kir, James P. White, Sandra Kleiner, L. Kazak, P. Cohen, Vickie E. Baracos, B. Spiegelman. Nature, 2014

617 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/4c106994e3889f8a1debe3bb0ca02d22f770fdba

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. P. Seale
2. S. Kajimura
3. L. Sidossis
4. B. Spiegelman
5. E. Rosen
6. Christoph Handschin
7. R. Scarpulla

In Physiology

1. P. Seale
2. S. Kajimura
3. B. Spiegelman
4. L. Sidossis
5. E. Rosen
6. R. Scarpulla
7. Christoph Handschin
8. G. Hotamışlıgil

Citations in the corpus

• Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. (2015, positive): “Spiegelman and colleagues reported that tumor-derived parathyroid hormone–related protein (PTHrP) promotes WAT browning and increased energy expenditure in a Lewis lung carcinoma model (65).”
• Brown and beige fat: Physiological roles beyond heat-generation (2015, background): “In addition, Parathyroid hormone-related protein (PTHrP) derived from the Lewis lung carcinoma potently promotes beige adipocyte biogenesis (Kir et al., 2014).”