Structure of the Bacterial RNA Polymerase Promoter Specificity σ Subunit

By E. Campbell, Oriana Muzzin, M. Chlenov, Jing L Sun, C. Olson, O. Weinman, Michelle Trester-Zedlitz, S. Darst. 2002

443 citations recorded by the source corpus.

Subfields: Ecology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4b85b3e49caa332e38b89de60d51ef9126126f7c

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In Genetics

1. R. Ebright
2. S. Darst

In Molecular Biology

1. Catherine L. Lawson
2. Helen M. Berman
3. David Swigon
4. R. Ebright
5. S. Darst
6. S. Parasuraman
7. G. Sheldrick
8. Torsten Schwede

Citations in the corpus

• Catabolite activator protein: DNA binding and transcription activation. (2004, methodology): “By joining the crystal structures of the CAP–aCTD– DNA complex [44 ] and the sR4–( 35 element) complex [47 ] — simply superimposing DNA segments of the two structures to generate a single, continuous DNA segment having a site for CAP, a site for aCTD, and a 35 element, spaced as at lac or CC( 61.”
• Region 4 of σ as a target for transcription regulation (2003, background): “…s70 in recognition of the promoter -35 element (Gardella et al., 1989), and the Taq sA region 4–DNA co-crystal structure suggested that this residue plays a critical role in positioning another residue (E410) for direct contact with a conserved basepair in the -35 element (Campbell et al., 2002a).”