Modelling viral and immune system dynamics

By Alan S. Perelson. Nature reviews. Immunology, 2002

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Viral Mutation Rates (2010, background): “For instance, this figure, together with the rate of infection of new cells, is used to calculate the probability of specific mutations occurring within an infected individual (72) or to predict the outcome of lethal mutagenesis treatments (5).”
Can we believe the DAGs? A comment on the relationship between causal DAGs and mechanisms (2014, background): “An excellent review showing the usefulness of diﬀerential equations in biology is given by Perelson.”
Mechanisms of viral mutation (2016, background): “HIV-1 is a fastmutating virus and produces every possible single-base substitution (including AZT-resistance mutations) within a patient everyday [4].”
ON IDENTIFIABILITY OF NONLINEAR ODE MODELS AND APPLICATIONS IN VIRAL DYNAMICS (2011, background): “For example, consider the following HIV model [80]:”
A review of the recent contribution of systems thinking to operational research and management science (2010, methodology): “, 2004; Lane and Husemann, 2008; Wolstenholme, 1999a) and modelling the spread of diseases (Dangerfield, 1999; Homer and Hirsch, 2006; Perelson, 2002).”