Viral Mutation Rates
By Rafael Sanjuán, Miguel R. Nebot, Nicola Chirico, L. Mansky, R. Belshaw. Journal of Virology, 2010
1,226 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/dd1b0d41fe58a5adc6fd2149490f6bc545fe88db
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- Rachel T. Eguia
- Edward C. Holmes
- Rafael Sanjuán
- Etienne Simon-Loriere
- K. H. Crawford
- P. Domingo-Calap
- Siobain Duffy
- Jesse D. Bloom
Citations in the corpus
- Why are RNA virus mutation rates so damn high? (2018, background): “Additionally, replication time (generation time) may be a larger component of understanding virus evolvability than it has been given credit for-likely undervalued because of the difficulties in measuring that trait in multicellular organisms [24, 25] .”
- A human coronavirus evolves antigenically to escape antibody immunity (2020, background): “Strangely, the possibility of antigenic evolution by coronaviruses has received only modest attention, perhaps because coronaviruses have lower mutation rates than other RNA viruses [21,22].”
- Mechanisms of viral mutation (2016, methodology): “As discussed in previous work, the reliability of some of these rates is compromised by several sources of estimation error and bias [1].”
- VIBRANT: automated recovery, annotation and curation of microbial viruses, and evaluation of viral community function from genomic sequences (2020, background): “Viruses harbor vast potential for diverse genetic content, arrangement, and encoded functions [14 – 17].”
- Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization (2021, background): “The intrinsically high error rates of viral RNA-dependent RNA polymerases (RdRp) result in the stochastic introduction of mutations during viral genome replication with substitutions approaching a nucleotide change per genome for each round of replication (Sanjuán et al., 2010).”
- Why do RNA viruses recombine? (2011, background): “It may be that the mutation rates are normally so high in RNA viruses (at between 10 −6 and 10 −4 mutations per nucleotide per cell infectio”
- Seed Transmission of Tobamoviruses: Aspects of Global Disease Distribution (2017, background): “Tropical soda apple mosaic virus (TSAMV) Solanaceae + >40% + 1–16% [127]”