Friends or foes — bipolar effects of the tumour stroma in cancer

By M. Mueller, N. Fusenig. Nature Reviews. Cancer, 2004

1,882 citations recorded by the source corpus.

Subfields: Cancer Research, Oncology

View Paper: https://www.semanticscholar.org/paper/4ac7f44fbe76a1b878509ec5587b713fd0fc8f7d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. R. Weinberg
2. Raghu Kalluri
3. M. Swartz
4. H. Wiig
5. M. Zeisberg
6. David J. Mooney
7. Y. Surh
8. A. Richardson

In Oncology

1. R. Weinberg
2. Raghu Kalluri
3. M. Zeisberg
4. H. Wiig
5. T. Onder
6. C. Scheel
7. Y. Surh
8. A. Richardson

Citations in the corpus

• Matrix metalloproteinases and tumor metastasis (2006, background): “However, elsewhere in this issue as well as in recent reviews is a detailed coverage of stromal MMPs and their contributions to tumorstroma interactions [7, 8, 13].”
• Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence (2006, neutral): “As it is becoming increasingly clear that stromal tissue is an indispensable player in neoplastic transformation and metastasi”
• A Six-Gene Signature Predicts Survival of Patients with Localized Pancreatic Ductal Adenocarcinoma (2010, background): “As the tumor microenvironment is increasingly recognized to play a critical role in tumorigenesis [30–33], tissues were macrodissected in order to preserve the normal adjacent tissue and stroma of the tumors.”
• Interactions Between the Immune System and Cancer: A Brief Review of Non-spatial Mathematical Models (2011, background): “In the last 20 years, it has become evident that the oversimplified concept of a single type of normal cell is inadequate; interactions among multiple cell types and chemicals play fundamental roles in the initiation and progression of tumors (Kammertoens et al. 2005; Mueller and Fusenig 2004).”
• Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. (2006, result): “Our findings support many published studies on tumor and stroma interaction (Mueller and Fusenig, 2004), which suggest that the metastatic propensity of HCC both is inherent to the tumor cell and is influenced by the local environmental status of metastatic sites.”
• Cysteine cathepsins: From structure, function and regulation to new frontiers (2011, background): “The cancer state is currently viewed as a product of its microenvironment [343].”