Nonalcoholic Steatohepatitis: Definition and Pathology

By E. Brunt. Seminars in liver disease (Print), 2001

1,008 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/4a93f7c469db264d42e3f49914a9b7e784f45ee5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. J. Clark
2. E. Brunt
3. A. McCullough
4. R. Lopez
5. S. Dasarathy
6. A. Khiyami
7. R. Joseph
8. Jaividhya Dasarathy

In Hepatology

1. J. Clark
2. A. McCullough
3. R. Lopez
4. S. Dasarathy
5. A. Khiyami
6. R. Joseph
7. Jaividhya Dasarathy
8. Shira Zelber-Sagi

In Pathology and Forensic Medicine

1. J. Clark
2. A. McCullough
3. S. Dasarathy
4. R. Lopez
5. A. Khiyami
6. R. Joseph
7. Jaividhya Dasarathy
8. Shira Zelber-Sagi

Citations in the corpus

• Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms (2005, neutral): “using the criteria described by Brunt [22].”
• The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. (2006, methodology): “Patients with NASH disease are evaluated histologically by grading the extent of hepatocyte ballooning, steatosis, and lobular inflammation (Brunt, 2001; 2004); the modified Brunt criteria were used to grade the steatohepatitis in Pemt 2 / 2 mice.”
• The Epidemiology of Nonalcoholic Fatty Liver Disease in Adults (2006, background): “NAFLD is characterized pathologically by macrovesicular steatosis, mild diffuse lobular mixed acute and chronic inflammation, perivenular and zone 3 perisinusoidal collagen deposition, hepatocyte ballooning, poorly formed Mallory’s hyaline, vacuolated nuclei in periportal hepatocytes, lobular lipogr”
• Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings (2011, background): “’’ It is, however, increasingly apparent from ongoing and published studies that the numeric value of the composite NAS is considered by some investigators to be either ‘‘synonymous’’ with, or actually a replacement for, a microscopic diagnosis that is based on overall pattern of injury as well as t”
• The prevalence and etiology of elevated aminotransferase levels in the United States (2003, background): “, bridging fibrosis and cirrhosis) may accompany seemingly mild aminotransferase elevations (3, 6, 7).”
• Diagnostic value of a computerized hepatorenal index for sonographic quantification of liver steatosis. (2009, methodology): “For patients with nonalcoholic fatty liver disease, the extent of liver steatosis and the degree of fibrosis and necroinflammatory activity were assessed histologically according to the Brunt [23, 24] criteria.”
• Validity of real time ultrasound in the diagnosis of hepatic steatosis: A prospective study (2009, methodology): “The diagnosis of NASH and steatosis were made using previously described criteria [21].”
• The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. (2003, neutral): “NASH is a clinicopathological syndrome that is closely associated with obesity, insulin resistance, and type 2 diabetes (14).”
• Histopathology of pediatric nonalcoholic fatty liver disease (2005, neutral): “5) 1 (6) 9 (53) 2 (4) Other 1 (1) 0 (0) 0 (0) 0 (0) 1 (2) BMI (kg/m2) Mean (SD) 31.”