A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus

By L. DeGiorgio, K. Konstantinov, Sunhee C. Lee, J. Hardin, B. Volpe, B. Diamond. Nature Medicine, 2001

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The role of immune dysfunction in the pathophysiology of autism (2011, neutral): “Such fetal brain-specific antibodies could alter neurodevelopment as is seen in systemic lupus erythematosis (SLE) (DeGiorgio et al., 2001; Lee et al., 2009).”
Review: Environmental exposure to mercury and its toxicopathologic implications for public health (2003, background): “It has been demonstrated that the pentapeptide Asp/Glu-Trp-Asp/Glu-Tyr-Ser/Gly is a molecular mimic of dsDNA (DeGiorgio et al., 2001).”
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. (2008, background): “Interestingly, anti-DNA antibodies can cross-react with glutamate receptors (37).”
Lysosomes as a therapeutic target (2019, background): “Neurological autoimmunity against various proteins, such as myelin in MS or N methyl d aspartate receptor in neuropsychiatric lupus 62, 123, 124 , can affect various structures within the CNS and peripheral nervous system, with diverse consequences.”