Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury.
By Dustin J. Donnelly, P. Popovich. Experimental Neurology, 2008
989 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Pathology and Forensic Medicine, Surgery
View Paper: https://www.semanticscholar.org/paper/70febdd6351d19320e7d5d52064f9facad54134e
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In Cellular and Molecular Neuroscience
In Pathology and Forensic Medicine
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Citations in the corpus
- Macrophage activation and its role in repair and pathology after spinal cord injury. (2015, background): “…the kinetics and magnitude of the macrophage response have been observed between different strains and species of animals (and humans); however, these cellular reactions are widely recognized as being pivotal in the pathological sequelae of all forms of mammalian SCI (Donnelly and Popovich, 2008).”
- Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord (2009, background): “, 2004), chronic inflammation is a hallmark of spinal contusion/compression pathology, and, in all examples of clinical and experimental SCI, macrophages dominate the lesion site indefinitely (Fleming et al., 2006; Chang, 2007; Donnelly and Popovich, 2008).”
- From basics to clinical: a comprehensive review on spinal cord injury. (2014, background): “inflammation also plays an important role in neural tissue repair (Donnelly and Popovich, 2008).”
- Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms (2019, background): “There are multiple cell types involved in the inflammatory response following injury including neutrophils, resident microglia, and astrocytes, dendritic cells (DCs), bloodborn macrophages, B- and T-lymphocytes (189) (Figure 4).”
- Repertoire of microglial and macrophage responses after spinal cord injury (2011, background): “The influx of inflammatory monocytes into the injured spinal cord coincides with neutrophil infiltration into the cor”