Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction

By H. Shimeno, S. Soeda, M. Sakamoto, T. Kouchi, Takashi Kowakame, T. Kihara. 1998

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Mitochondrial Ceramide and the Induction of Apoptosis (2005, background): “As stated above, mitochondria contain the enzymes responsible for ceramide synthesis and hydrolysis, namely, ceramide synthase and ceramidase (El Bawab et al., 2000; Shimeno et al., 1998; Bionda et al., 2004).”
A ceramide-centric view of insulin resistance. (2012, background): “One possible explanation for this observation is that the import of acyl-CoAs into the inner mitochondrial membranemay be important for producing particular pools of ceramide, as most of the de novo synthesis have been found on mitochondrial membranes (Bionda et al., 2004; Shimeno et al., 1998).”