Loss of Function of a Proline-Containing Protein Confers Durable Disease Resistance in Rice

By S. Fukuoka, N. Saka, H. Koga, K. Ono, Takehiko Shimizu, K. Ebana, N. Hayashi, A. Takahashi, H. Hirochika, K. Okuno and 1 more. Science, 2009

614 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/490eb577fd9cd403a67a4739ec4987024a87db86

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. M. Thomson
2. Jeffery L. Dangl
3. G. Eizenga
4. Jonathan D. G. Jones
5. A. McClung

In Plant Science

1. M. Thomson
2. G. Eizenga
3. Jeffery L. Dangl
4. R. V. D. van der Hoorn
5. Jonathan D. G. Jones
6. A. McClung
7. Aziiba Emmanuel Asibi
8. Takuji Sasaki

Citations in the corpus

• Functional complementation of rice blast resistance gene Pi-kh(Pi54) conferring resistance to diverse strains of Magnaporthe oryzae (2011, neutral): “Pi5 (Lee et al. 2009), pi21 ( Fukuoka et al. 2009 ) and Pit (Hayashi and Yoshida 2009).”
• Development of genome-wide SNP assays for rice (2010, background): “1) (Ashikari and Matsuoka 2006, Fukuoka et al. 2009, 2010, Tanksley and McCouch 1997, Yara et al. 2010).”
• Defended to the Nines: 25 Years of Resistance Gene Cloning Identifies Nine Mechanisms for R Protein Function[OPEN] (2018, background): “Analogous to the mlo mechanism, the recessive resistance toward rice blast is conferred by a loss-of-function mutation in Pi21, ageneencodingaHMAdomainprotein thatacts tosuppress the plant defense response (Fukuoka et al., 2009).”
• Intracellular innate immune surveillance devices in plants and animals (2016, background): “But why do pathogens evolve effectors that interact withHMAdomain proteins? A clue is provided by the observation that the recessive disease-resistance gene Pi21 contains an HMA domain (91).”
• Rice Annotation Project Database (RAP-DB): An Integrative and Interactive Database for Rice Genomics (2013, methodology): “In addition, by specifying any two SSR markers, users can obtain the data between them, which would be helpful, for example, to search for candidate genes of the target region detected by quantitative trait locus (QTL) analysis (Konishi et al. 2006, Fukuoka et al. 2009).”
• Rice Blast: A Disease with Implications for Global Food Security (2019, background): “Pi21 appears to slow the plant’s defense responses, which may support optimization of defense mechanisms [156].”