The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough
By J. Heidelberg, Rekha Seshadri, S. A. Haveman, Christopher L. Hemme, Ian T. Paulsen, J. Kolonay, Jonathan A. Eisen, N. Ward, B. Methé, L. Brinkac and 25 more. Nature Biotechnology, 2004
646 citations recorded by the source corpus.
Desulfovibrio vulgaris Hildenborough is a model organism for studying the energy metabolism of sulfate-reducing bacteria (SRB) and for understanding the economic impacts of SRB, including biocorrosion of metal infrastructure and bioremediation of toxic metal ions. The 3,570,858 base pair (bp) genome sequence reveals a network of novel c-type cytochromes, connecting multiple periplasmic hydrogenases and formate dehydrogenases, as a key feature of its energy metabolism. The relative arrangement of genes encoding enzymes for energy transduction, together with inferred cellular location of the enzymes, provides a basis for proposing an expansion to the 'hydrogen-cycling' model for increasing energy efficiency in this bacterium. Plasmid-encoded functions include modification of cell surface components, nitrogen fixation and a type-III protein secretion system. This genome sequence represents a substantial step toward the elucidation of pathways for reduction (and bioremediation) of pollutants such as uranium and chromium and offers a new starting point for defining this organism's complex anaerobic respiration.
Subfields: Environmental Chemistry, Environmental Engineering, Health, Toxicology and Mutagenesis
View Paper: https://www.semanticscholar.org/paper/48d1b2822fc56fd77d47030223644397ae69f454
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In Environmental Engineering
Citations in the corpus
- Respiration of metal (hydr)oxides by Shewanella and Geobacter: a key role for multihaem c-type cytochromes (2007, background): “…membrane, where they are positioned to interact with extracellular substrates, whereas most membrane c-Cyts found in other bacteria, including multihaem c-Cyts in sulphate respiring bacteria such as Desulfovibrio, are associated with the cytoplasmic or inner membranes (Heidelberg et al., 2004).”
- Occurrence of benthic microbial nitrogen fixation coupled to sulfate reduction in the seasonally hypoxic Eckernförde Bay, Baltic Sea (2012, background): “Two of the organisms that clustered with September nifH sequences were SRB, namelyDesulfovibrio vulgaris (Postgate, 1984; Heidelberg et al., 2004) andDesulfonema limicola(Widdel, 1989; Fukui et al., 1999).”