Human L1 Retrotransposition: cisPreference versus trans Complementation

By Wei Wei, N. Gilbert, S. Ooi, J. F. Lawler, E. Ostertag, Haig H. Kazazian, J. Boeke, J. V. Moran. Molecular and Cellular Biology, 2001

629 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Haplotype-resolved diverse human genomes and integrated analysis of structural variation (2021, background): “%) with defective ORFs, suggesting either transcomplementation ( 56 ) or polymorphisms leading to the recent demise of these active source elements.”
DNA hypomethylation and human diseases. (2007, neutral): “1 million copies [74,75].”
DNA methylation in cancer: too much, but also too little (2002, background): “There have been occasional reports of cancer-associated retrotransposition-like insertions involving LINE-1 sequences (Miki et al., 1992; Morse et al., 1988), and they may mobilize cellular RNAs at low frequencies (Wei et al., 2001).”