Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

By M. Kay, J. Glorioso, L. Naldini. Nature Medicine, 2001

1,397 citations recorded by the source corpus.

Subfields: Genetics, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4859c97a689409e17e787604677cd95a85cc874a

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In Molecular Biology

1. G. Storm

Citations in the corpus

• Endosomal escape pathways for delivery of biologicals. (2011, background): “Despite the efforts given in vector technology, development of methods for efficient and protected delivery of therapeutic agents to the target cells still remains a main issue [3,4].”
• Gene therapy clinical trials worldwide to 2017: An update (2018, background): “By contrast, viral systems, which are commonly modified to render them replication‐incompetent, are markedly more efficient and exploit favourable aspects of virus biology.(121,122) Depending on the nature of the modification required, however, transient delivery of nucleic acids, oligonucleotides, ”