Lecticans: organizers of the brain extracellular matrix

By Y. Yamaguchi. Cellular and Molecular Life Sciences (CMLS), 2000

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Diffusion in Brain Extracellular Space (2008, positive): “The ECM is composed of negatively charged glycosaminoglycans and proteoglycans (156, 212, 269, 322, 421).”
The blood-brain barrier: an engineering perspective (2013, background): “Typical time averaged values of shear stress are 4–30 dynes cm−2 in the arterial circulation and 1–4 dynes cm−2 in the venous circulation (Turitto, 1982; Kamiya et al., 1984; Papaioannou and Stefanadis, 2005; Koutsiaris et al., 2007; Dolan et al., 2013).”
An Introduction to Proteoglycans and Their Localization (2012, background): “For example, the large hyaluronanbinding (aggregating) proteoglycans, the lecticans (Yamaguchi 2000), consist of four members, aggrecan, versican, neurocan, and brevican.”
From basics to clinical: a comprehensive review on spinal cord injury. (2014, background): “Moreover, in the adult, CSPGs promote brain synapses stability (Yamaguchi, 2000) and limit plasticity (Corvetti and Rossi, 2005).”
Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions (2013, background): “HA can be catabolized by a number of enzymes in the hyaluronidase (HAase) family.”