Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness

By Brenda K. Eustace, T. Sakurai, J. Stewart, Dean Yimlamai, C. Unger, C. Zehetmeier, B. Lain, C. Torella, Stefan W. Henning, G. Beste and 4 more. Nature Cell Biology, 2004

609 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/47940c68c182faa3cbefe51cdef487a586396dde

How researchers see this paper

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In Materials Chemistry

1. Susan Lindquist
2. L. Whitesell

In Molecular Biology

1. Mikko Taipale
2. L. Whitesell
3. Susan Lindquist
4. Richard I. Morimoto

Citations in the corpus

• HSP90 at the hub of protein homeostasis: emerging mechanistic insights (2010, background): “, where it matures metalloproteinase 2, mediating tumour cell invasivenes”
• HSP90 and the chaperoning of cancer (2005, background): “Secretion of HSP90α into the extracellular matrix surrounding tumour cells has been reported and seems to assist in the activation of matrix metalloproteinase-2 as well as contributing to tumour cell invasivenes”