Mechanisms of pre‐apoptotic calreticulin exposure in immunogenic cell death
By T. Panaretakis, Oliver Kepp, U. Brockmeier, A. Tesnière, Anneli Bjorklund, D. C. Chapman, Michael Durchschlag, N. Joza, G. Pierron, P. van Endert and 5 more. EMBO Journal, 2009
804 citations recorded by the source corpus.
Subfields: Cell Biology, Epidemiology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/47927e831e7505f53a0bed366e9f10e7aeb626be
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In Cell Biology
- Guido Kroemer
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In Epidemiology
In Molecular Biology
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Citations in the corpus
- A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death (2012, positive): “Importantly, in the case of ecto-CRT triggered by anthracyclines, both ER stress and reactive oxygen species (ROS) production have been found to be mandatory (Panaretakis et al , 2009).”
- Immune parameters affecting the efficacy of chemotherapeutic regimens (2011, background): “Endoplasmic reticulum stress causes sublethal activation of caspase-8 and exocytosis of endoplasmic reticulum-derived vesicles, calreticulin, which is usually secluded in the lumen of the endoplasmic reticulum and relocates to the outer surface of the plasma membrane before cells become apoptotic”
- Immunogenic death of colon cancer cells treated with oxaliplatin (2010, methodology): “In some experiments, cells were exposed to recombinant CRT, at 3 mg per 10(6) cells in phosphate buffered saline (PBS) on ice for 30min, as described earlier (Obeid et al., 2007b; Panaretakis et al., 2009), followed by three washes.”