Otto Warburg's contributions to current concepts of cancer metabolism

By W. Koppenol, P. L. Bounds, C. V. Dang. Nature Reviews. Cancer, 2011

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The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression (2019, background): “…that oxidative phosphorylation (OXPHOS) and a normal Krebs cycle (TCA cycle) persist in the vast majority, if not in all malignant tumors, that is, most cancers exhibit the Warburg effect while retaining mitochondrial respiration (for reviews, see e.g. Koppenol et al. 2011;Vaupel and Mayer 2012).”
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B-cells (2012, neutral): “Together with the well-known Warburg effect (Koppenol et al., 2011; Vander Heiden et al., 2009; Warburg, 1956; Warburg et al., 1924) and numerous other alterations in the central metabolism of cancers (King et al.”
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate (2012, background): “An extension of this hypothesis was that dysfunctional mitochondria caused cancer (Koppenol et al., 2011).”
Understanding the intersections between metabolism and cancer biology (2017, neutral): “This route of ATP production yields less ATP per mole of glucose, but allows fast ATP generation even in low oxygen (Koppenol et al., 2011).”