Tau and neurodegenerative disease: the story so far

By K. Iqbal, Fei Liu, C. Gong. Nature Reviews Neurology, 2016

720 citations recorded by the source corpus.

Subfields: Molecular Biology, Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/4741747431cac15fd1f56614d048bf04022c2b79

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Howard Y. Chang
2. Luke A. Gilbert
3. Jonathan S. Weissman
4. Bradley E. Bernstein
5. David P. Bartel
6. Pedro J. Batista
7. Johannes Rinn
8. Jennifer A. Doudna

In Neurology

1. M. Hasegawa

Citations in the corpus

• The world of protein acetylation. (2016, background): “This fibril formation and subsequent formation of insoluble plaques is a major factor in the etiology of Alzheimer's and related diseases, termed tauopathies [442].”
• Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease (2018, background): “In AD brains, 3R and 4R tau is accumulated in a hyperphosphorylated state in the pathological inclusions (Goedert, 1993; Goedert et al., 1996; Serrano-Pozo et al., 2011; Iqbal et al., 2016).”
• Genome-wide Programmable Transcriptional Memory by CRISPR-based Epigenome Editing (2021, methodology): “We next applied CRISPRoff-mediated editing of iPSC-derived neurons to silence MAPT, a gene that encodes the Tau protein and is implicated in various neurological diseases (Iqbal et al., 2016).”