Bacterial Quorum Sensing in Pathogenic Relationships

By T. D. de Kievit, B. Iglewski. Infection and Immunity, 2000

1,145 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/46e85ff0a1cff58ccd2dcaec4db04026d231d101

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. M. Givskov
2. Bernhard O. Palsson
3. Jason A. Papin
4. Matthew A. Oberhardt
5. B. Bassler
6. Costas D. Maranas
7. Jennie L. Reed
8. Jonathan M. Monk

In Genetics

1. B. Bassler
2. Klaus Winzer
3. Miguel Cámara
4. T. Defoirdt
5. Jason A. Papin
6. N. Boon
7. W. Verstraete
8. Peter Bossier

In Molecular Biology

1. B. Bassler
2. M. Givskov
3. Jason A. Papin
4. Bernhard O. Palsson
5. Søren Molin
6. M. Parsek
7. Matthew A. Oberhardt
8. Niels Høiby

Citations in the corpus

• Structural identification of a bacterial quorum-sensing signal containing boron (2002, background): “Community cooperation probably enhances the effectiveness of processes such as bioluminescence, virulence factor expression, antibiotic production and biofilm developmen”
• Disruption of bacterial quorum sensing: an unexplored strategy to fight infections in aquaculture (2004, background): “Quorum sensing systems are found in a still growing list of bacteria that are pathogenic to plants, animals and humans (for reviews see De Kievit and Iglewski, 2000; Williams et al., 2000).”
• Look who's talking: communication and quorum sensing in the bacterial world (2007, background): “…N- (3-oxododecanoyl)-L-homoserine lactone (3-oxo-C12- HSL; Pearson et al. 1994) and together with the LasR regulates the production of, for example, virulence factors including elastase, the LasA protease, alkaline protease and exotoxin A (Gambello & Iglewski 1991; De Kievit & Iglewski 2000).”
• Applications of genome-scale metabolic reconstructions (2009, background): “Also, meaningful modeling of multi-species interactions often necessitates augmentation of a metabolic GENRE with some regulatory and signaling information, which further increases the complexity and difficulty of this type of modeling (de Kievit and Iglewski, 2000).”
• Pseudomonas aeruginosa: new insights into pathogenesis and host defenses. (2013, background): “Pseudomonas aeruginosa produces two elastases, LasA and LasB, which are regulated by the lasI quorum-sensing system and secreted via type 2 secretion systems (Toder et al., 1994; de Kievit & Iglewski, 2000).”