The collagen family.

By Sylvie Ricard-Blum. Cold Spring Harbor Perspectives in Biology, 2011

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Overview of the matrisome--an inventory of extracellular matrix constituents and functions. (2012, background): “…proteolytic processes play roles in ECM turnover and are thought to release ECM-bound growth factors and also to expose cryptic activities in the ECM (Mott and Werb 2004; Ricard-Blum 2011), including the release of antiangiogenic inhibitors (Bix and Iozzo 2005; Nyberg et al. 2005; Hynes 2007).”
Application of Collagen Scaffold in Tissue Engineering: Recent Advances and New Perspectives (2016, background): “Collagen represents the most abundant structural protein, accounting for approximately 30% of total body proteins in mammals [14].”
Collagen in Wound Healing (2021, background): “These fragments are of interest in curbing angiogenesis in several pathological conditions [12,19,34].”