Dissecting direct reprogramming through integrative genomic analysis

By Tarjei S. Mikkelsen, J. Hanna, Xiaolan Zhang, Manching Ku, Marius Wernig, Patrick Schorderet, Bradley E. Bernstein, R. Jaenisch, Eric S. Lander, Alexander Meissner. Nature, 2008

619 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/453c2ff87345ce8d8518e8077a828459c9b9a4e8

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In Molecular Biology

1. Sheng Ding
2. Yan Shi
3. Hans Robert Schöler
4. C. Desponts
5. J. Do
6. H. S. Hahm

Citations in the corpus

• Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. (2008, background): “…the first small molecule of its type to show an effect on reprogramming, as most of the other small molecules found up to date appear to directly modify the epigenetic status of the cell: i.e., BIX (Shi et al., 2008), valproic acid (Huangfu et al., 2008), and 50azacytidine (Mikkelsen et al., 2008).”
• Optimal-transport analysis of single-cell gene expression identifies developmental trajectories in reprogramming (2019, neutral): “Some studies (Mikkelsen et al., 2008; O’Malley et al., 2013; Parenti et al., 2016) have noted strong upregulation of several lineage-specific genes from unrelated lineages (e.”