Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study.

By R. Peila, B. Rodríguez, Lenore J. Launer. Diabetes, 2002

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Diabetes mellitus and risk of dementia: A meta‐analysis of prospective observational studies (2013, background): “Peila et al.(10) have also reported a high association (a fivefold increase) between AD and diabetes, particularly among carriers of the APOE e4 allele.”
Effects of central arterial aging on the structure and function of the peripheral vasculature: implications for end-organ damage. (2008, background): “Vascular cognitive impairment and Alzheimer’s disease have been related to cardiovascular disease risk factors, including increased SBP and pulse pressure, elevated fasting glucose and LDL cholesterol, reduced HDL cholesterol, and reduced physical activity in midlife (10, 42, 44, 70, 73, 74, 89, 97)”
Epidemiology of Alzheimer Disease (2012, neutral): “Pendlebury and Rothwell (2009) analyzed data from several hospital-and population-based cohorts (7511 patients) and estimated a frequency of new-onset dementia to be approximately 7% following a first stroke.”