Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.
By D. Tan, R. Reiter, L. Manchester, Mei-ting Yan, M. El-Sawi, R. Sainz, J. Mayo, R. Kohen, M. Allegra, R. Hardeland. Current Topics in Medicinal Chemistry, 2002
1,065 citations recorded by the source corpus.
Subfields: Biophysics, Endocrine and Autonomic Systems, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/44b1bdc27f47272db34c58016a0495d4b3a3e408
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In Biophysics
In Endocrine and Autonomic Systems
In Organic Chemistry
Citations in the corpus
- Melatonin in plants (2008, background): “oxidative damage (6) by increasing the efficiency of mitochondrial electron transport chain thereby lowering electron leakage and thus reducing free radical generation (Tan et al. 2002; Kładna et al. 2003; Rodriguez et al. 2004; Leon et al. 2005).”
- One molecule, many derivatives: A never‐ending interaction of melatonin with reactive oxygen and nitrogen species? (2007, background): “Melatonin is also a potent, endogenously produced and diet-derived free radical scavenger and broad-spectrum antioxidant [6, 7].”
- Melatonin: a multitasking molecule. (2010, background): “Since then, this action of melatonin has been repeatedly confirmed (Tan et al., 2002).”
- Extrapineal melatonin: sources, regulation, and potential functions (2014, background): “Two main mechanisms are involved in these actions of melatonin: (1) a direct free radical scavenger activity [55] that generates a series of intermediates during its interaction with ROS and nitrogen species, all of them which are also free radical”