Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signals.
By J. Flynn, S. Neher, Y. I. Kim, R. Sauer, T. Baker. Molecules and Cells, 2003
609 citations recorded by the source corpus.
Subfields: Cell Biology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/42e90e7d640806836a12dfe432d97c62b08f8a7d
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In Cell Biology
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Citations in the corpus
- AAA+ proteins: have engine, will work (2005, background): “Other motifs that direct proteins for degradation by ClpXP in Escherichia coli were identified by examining the sequences of proteins that accumulate in a proteolytically inactive ClpXP substrate tra”
- Proteasomes and their kin: proteases in the machine age (2004, methodology): “However, in a recent experiment, Flynn et al.62 used a protease-dead version of ClpXP to capture intact substrates in vivo (see figure; see also REF.”