Microfluidic diagnostic technologies for global public health

By Paul Yager, T. Edwards, Elain Fu, Kristen L. Helton, K. Nelson, Milton R. Tam, B. Weigl. Nature, 2006

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Advances in Microfluidic PCR for Point-of-Care Infectious Disease Diagnostics (2011, background): “N IH -PA Author M anuscript N IH -PA Author M anuscript greater (Urdea et al. , 2006, Yager et al. , 2008, Yager et al. , 2006).”
Advances in paper-based point-of-care diagnostics. (2014, background): “More than 95% of the deaths occur in developing countries due to the lack of cost-effective medical interventions (Lee et al., 2010; Yager et al., 2006).”
Point-of-care diagnostics for global health. (2008, methodology): “These sample-preparation tasks are often difficult to perform in laboratories in low-resource settings and are impossible outside of laboratories, so some of the greatest advances in moving diagnostics to the periphery of the health care system can be made in this way (3).”
Surface Engineering and Patterning Using Parylene for Biological Applications (2010, background): “Microfluidic systems hold promise for portable bioassays and interrogation of biomolecules with minimal reagent and sample volume consumption [8-10].”
Fluorescent magnetic bead and cell differentiation/counting using a CMOS SPAD matrix (2012, neutral): “Most importantly , external hardware and high end microscopic setups are still essential for successful implementation of these methods [12] [13] [14] [15] [16].”