Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

By Jian-Wen Han, Houfeng Zheng, Yong Cui, Liangdan Sun, D. Ye, Zhilin Hu, Jin-hua Xu, Z. Cai, Wei Huang, Guoping Zhao and 56 more. Nature Genetics, 2009

950 citations recorded by the source corpus.

Subfields: Immunology, Rheumatology

View Paper: https://www.semanticscholar.org/paper/41e810d11a6084cdd07985db9afa2143878deff5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. N. Mizushima
2. Beth Levine
3. Herbert W. Virgin
4. T. Kanai
5. K. Matsuoka

Citations in the corpus

• Autophagy in immunity and inflammation (2011, background): “Genome-wide association studies have linked several single nucleotide polymorphisms (SNPs) in ATG5 to SLE susceptibility [91] [92] [93] .”
• A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. (2010, background): “For example, rs13385731 has been associated with SLE (Han et al. 2009) and is located within a VDR interval in the first intron of RASGRP3 (Fig.”
• Impacts of Neanderthal-introgressed sequences on the landscape of human gene expression (2017, neutral): “111), which lies within the lysosomal transporter-encoding geneSLC15A4 and is associated with systemic lupus erythematosus (Table 1; Han et al., 2009).”
• Multiple common variants for celiac disease influencing immune gene expression (2010, positive): “Genetic variation in ETS1 has recently been reported to be associated with systemic lupus erythematosus (SLE) in the Chinese population, although it is not associated with SLE in European population”
• New IBD genetics: common pathways with other diseases (2011, background): “A Caucasian SLE scan demonstrated association within ATG5 itself (rs573775),(86) while in a Chinese SLE scan the most strongly associated SNP was within 26 kb of the Crohn’s disease SNP.(88)”