Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock*

By M. Mikkelsen, A. Miltiades, D. Gaieski, M. Goyal, B. Fuchs, C. Shah, S. Bellamy, J. Christie. Critical Care Medicine, 2009

930 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Epidemiology, Surgery

View Paper: https://www.semanticscholar.org/paper/41e42cacaab718b5474640110ce54eb2daeea947

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. A. Rhodes
2. Jean-Louis Vincent
3. M. Cecconi

In Epidemiology

1. Michael R. Pinsky
2. A. Rhodes
3. Jean-Louis Vincent
4. J. Teboul
5. M. Cecconi

In Surgery

1. Michael R. Pinsky
2. Jean-Louis Vincent
3. J. Teboul

Citations in the corpus

• Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine (2014, background): “Many studies have confirmed the association between initial serum lactate level and mortality independently of clinical signs of organ dysfunction in patients not only with severe sepsis [47], but also those in cardiogenic shock [48].”
• Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial. (2010, background): “Interestingly, the prognostic value of lactate levels seems to be independent from the underlying critical illness (6) or the presence of shock or organ failure (7).”