Retinal repair by transplantation of photoreceptor precursors

By Robert E. MacLaren, R. Pearson, A. Macneil, R. Douglas, T. Salt, M. Akimoto, A. Swaroop, J. Sowden, R. Ali. Nature, 2006

1,028 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Modeling early retinal development with human embryonic and induced pluripotent stem cells (2009, background): “(32) demonstrated that cells from a specific stage of mouse retinal development were capable of functionally integrating into degenerate adult mouse retinas.”
Transplantation of human embryonic stem cells derived photoreceptors restores some visual function in Crx deficient mice (2009, positive): “Previous results have shown that mouse photoreceptors incorporate effectively in adult retinas when transplanted to the subretinal space (MacLaren et al., 2006).”
Self-formation of optic cups and storable stratified neural retina from human ESCs. (2012, background): “Because a previous mouse study has shown that Nrl photoreceptor progenitors have the ability to integrate into the host retina (MacLaren et al., 2006), Nrl photoreceptors generated from hESCs in our 3D culture (e.”