Calcium-dependent protein kinase/NADPH oxidase activation circuit is required for rapid defense signal propagation

By Ullrich Dubiella, Heike Seybold, Guido Durian, Eileen Komander, R. Lassig, C. Witte, Waltraud X. Schulze, T. Romeis. Proceedings of the National Academy of Sciences of the United States of America, 2013

660 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/4125202e67ca3c5025c9ad3d8bd90a6d626eeb1c

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Citations in the corpus

The FLS2-associated kinase BIK1 directly phosphorylates the NADPH oxidase RbohD to control plant immunity. (2014, background): “As shown in our study, the Ser39 and likely Ser343 phosphorylation is BIK1 specific and calcium independent, whereas the Ser148 phosphorylation shown in previous reports is likely calcium dependent and CPK specific (Kobayashi et al., 2007; Dubiella et al., 2013; Gao et al., 2013).”
Signaling mechanisms in pattern-triggered immunity (PTI). (2015, background): “Several CDPK substrates were identified, such as RBOHD as a substrate of CPK5, and tomato ACS2 as a substrate of tomato CDPK2 (Kamiyoshihara et al., 2010; Boudsocq and Sheen, 2013; Dubiella et al., 2013; Schulz et al., 2013).”
ROS Regulation During Abiotic Stress Responses in Crop Plants (2015, background): “Ca2+ regulates NADPH oxidase-dependent ROS production by binding directly to the EF-hand motif in the N terminus of RBOH protein and/or regulating Ca2+-dependent phosphorylation medicated by CDPK (Ogasawara et al., 2008; Dubiella et al., 2013).”
Oxidative stress and antioxidative responses in plant-virus interactions (2016, neutral): “phosphorylation with ROS production [41,54, 143].”
Reactive oxygen species, abiotic stress and stress combination. (2017, background): “This flux directly activates RBOHs, and/or triggers a cascade of events that activates calcium-dependent protein kinases that phosphorylate and activate RBOHs (Miller et al., 2009; Mittler et al., 2011; Dubiella et al., 2013; Gilroy et al., 2014; Figure 4a).”
Direct regulation of the NADPH oxidase RBOHD by the PRR-associated kinase BIK1 during plant immunity. (2014, background): “PAMP treatment induces within 10 min the phosphorylation of the RBOHD residues S39, S148, S152, S163, S343, and S347 (Benschop et al., 2007; Nühse et al., 2007; Dubiella et al., 2013).”
Abiotic stress signaling and responses in plants (2016, background): “RbohD is phosphorylated by the calcium-dependent protein kinase CPK5, which can be activated by ROS and is required for systemic defense responses (Dubiella et al., 2013).”