Prevalence of Congenital Heart Defects in Metropolitan Atlanta, 1998–2005

By M. Reller, M. Strickland, Tiffany J. Riehle‐Colarusso, W. Mahle, Adolfo Correa. Jornal de Pediatria, 2008

1,117 citations recorded by the source corpus.

Objective To determine an accurate estimate of the prevalence of congenital heart defects (CHD) using current standard diagnostic modalities. Study design We obtained data on infants with CHD delivered during 1998–2005 identified by the Metropolitan Atlanta Congenital Defects Program, an active, population-based birth defects surveillance system. Physiologic shunts in infancy and shunts associated with prematurity were excluded. Selected infant and maternal characteristics of the cases were compared with those of the overall birth cohort. Results From 1998–2005 there were 398 140 births, of which 3240 infants had CHD, for an overall prevalence of 81.4/10 000 births. The most common CHD were muscular ventricular septal defect, perimembranous ventricular septal defect, and secundum atrial septal defect, with prevalence of 27.5, 10.6, and 10.3/10 000 births, respectively. The prevalence of tetralogy of Fallot, the most common cyanotic CHD, was twice that of transposition of the great arteries (4.7 vs. 2.3/10 000 births). Many common CHD were associated with older maternal age and multiple-gestation pregnancy; several were found to vary by sex. Conclusion This study, using a standardized cardiac nomenclature and classification, provides current prevalence estimates of the various CHD subtypes. These estimates can be used to assess variations in prevalence across populations, time or space.

Subfields: Epidemiology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/40321954b383db4c984cbb281f51cf001a21d3f0

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In Epidemiology

1. Tiffany J. Riehle‐Colarusso
2. Adolfo Correa

In Pulmonary and Respiratory Medicine

1. Tiffany J. Riehle‐Colarusso
2. Adolfo Correa

Citations in the corpus

• Temporal Trends in Survival Among Infants With Critical Congenital Heart Defects (2013, neutral): “Survival status is determined via 3 possible methods: (1) review of available clinical records, (2) linkage with vital records from the state of Georgia, and (3) linkage with the National Death Index.”
• Lifetime Prevalence of Congenital Heart Disease in the General Population From 2000 to 2010 (2014, background): “In the Quebec CHD database, as presented in the present study, we observed a prevalence of CHD in infancy that was remarkably close to the most commonly reported rate of birth prevalence of CHD in the United States.1 This finding supports the use of our data to estimate the number of adults with CHD”
• Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. (2011, result): “Our results confirm findings from the Metropolitan Atlanta Congenital Defects Program that routine use of echocardiography has increased diagnosis of minor defects (10).”
• Congenital Heart Defects in the United States: Estimating the Magnitude of the Affected Population in 2010 (2016, positive): “The estimated birth prevalence of CHD in the US is approximately 8–10 per 1,000 live births 1,2 and has increased over the last 30–40 years, driven largely by increasing prevalence and improved detection of less severe phenotypes such as ventricular septal defects and atrial septal defects.”