Ascorbate regulation and its neuroprotective role in the brain.
By M. Rice. Trends in Neurosciences, 2000
790 citations recorded by the source corpus.
Subfields: Developmental Neuroscience, Materials Chemistry, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/3fb67d655f4b23c337f23ea29c19245f3f11e3e5
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In Developmental Neuroscience
In Materials Chemistry
In Nutrition and Dietetics
Citations in the corpus
- Physiology of Astroglia. (2018, neutral): “are able to accumulate the dehydroascorbic acid derived from ROS oxidation and released by neurons and reduce it (using glutathione) to ascorbic acid (1464, 1886).”
- Astrocytes and Brain Injury (2003, background): “Like glutathione, ascorbate is an important antioxidant that is present in brain at millimolar concentrations (Rice, 2000).”
- Oxidative stress and neurodegeneration: where are we now? (2006, background): “Ascorbate concentrations in human CSF are higher than in plasma, and neurons and glia have transport systems that concentrate ascorbate even more, to millimolar intracellular levels (Rice 2000).”
- Vitamin C Function in the Brain: Vital Role of the Ascorbate Transporter (SVCT2) (2009, background): “A more severe stress of ischemia releases large amounts of ascorbate from brain cells [105], which is associated with glutamate uptake by neurons and glia [67,71].”