Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline.
By W. Hembree, P. Cohen-Kettenis, H. Delemarre-van de Waal, L. Gooren, W. Meyer, N. Spack, V. Tangpricha, Victor M. Montori. Journal of Clinical Endocrinology and Metabolism, 2009
975 citations recorded by the source corpus.
OBJECTIVE The aim was to formulate practice guidelines for endocrine treatment of transsexual persons. EVIDENCE This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe the strength of recommendations and the quality of evidence, which was low or very low. CONSENSUS PROCESS Committees and members of The Endocrine Society, European Society of Endocrinology, European Society for Paediatric Endocrinology, Lawson Wilkins Pediatric Endocrine Society, and World Professional Association for Transgender Health commented on preliminary drafts of these guidelines. CONCLUSIONS Transsexual persons seeking to develop the physical characteristics of the desired gender require a safe, effective hormone regimen that will 1) suppress endogenous hormone secretion determined by the person's genetic/biologic sex and 2) maintain sex hormone levels within the normal range for the person's desired gender. A mental health professional (MHP) must recommend endocrine treatment and participate in ongoing care throughout the endocrine transition and decision for surgical sex reassignment. The endocrinologist must confirm the diagnostic criteria the MHP used to make these recommendations. Because a diagnosis of transsexualism in a prepubertal child cannot be made with certainty, we do not recommend endocrine treatment of prepubertal children. We recommend treating transsexual adolescents (Tanner stage 2) by suppressing puberty with GnRH analogues until age 16 years old, after which cross-sex hormones may be given. We suggest suppressing endogenous sex hormones, maintaining physiologic levels of gender-appropriate sex hormones and monitoring for known risks in adult transsexual persons.
Subfields: Clinical Psychology, Molecular Biology, Social Psychology
View Paper: https://www.semanticscholar.org/paper/3f2f7b6c2d18b844c0def1215305e12639ed0d07
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Citations in the corpus
- Guidelines for psychological practice with transgender and gender nonconforming people. (2015, positive): “…health provider is encouraged due to the psychosocial implications, and is often also a required part of the medical treatment regimen that may be offered to TGNC adolescents (Coleman et al., 2012; Hembree et al., 2009), psychologists often play an essential role in assisting in this process.”
- Affirmative practice with transgender and gender nonconforming youth: Expanding the model. (2016, methodology): “…model is supported within clinical practice guidelines from major professional organizations, including the APA (2015), the WPATH (Coleman et al., 2012), the American Academy of Child and Adolescent Psychiatry (Adelson & AACAP CQI, 2012), and the Endocrine Society (Hembree et al., 2009).”
- Developing Allies to Transgender and Gender-Nonconforming Youth: Training for Counselors and Educators (2014, background): “Do kids take hormones? The WPATH (2012) standards of care and Endocrine Society guidelines (Hembree et al., 2009) do not recommend hormones until after age 16.”
- Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7 (2012, methodology): “The patient should continue to be monitored by physical examinations and laboratory testing on a regular basis, as outlined in the literature (Feldman & Safer, 2009; Hembree et al., 2009).”