Effect of an intensive glucose management protocol on the mortality of critically ill adult patients.

By J. Krinsley. Mayo Clinic proceedings, 2004

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ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiov (2007, methodology): “Krinsley (503), 2004 Retrospective 1600 Med-Surg ICU pts Historical control vs standardized glucose control protocol Historical 152 93 vs protocol 131 55 16 vs 18 Decreased mortality, renal insufficiency, and ICU length of stay were observed in the standardized insulin protocol compared with the his”
Variability of Blood Glucose Concentration and Short-term Mortality in Critically Ill Patients (2006, neutral): “001 Hospital stay, days 16 [9–34] 6 [3–14] 0.”
Glycemic variability: A strong independent predictor of mortality in critically ill patients* (2008, background): “Details of this program, and its outcomes, have been reported in earlier publications (9, 12).”
Severe hypoglycemia in critically ill patients: Risk factors and outcomes* (2007, background): “34% among the patients in the intervention group (17).”
Guidelines for Perioperative Care in Elective Colonic Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations (2012, background): “Treatment of hyperglycaemia in surgical patients in the Intensive Care Unit (ICU) consistently shows improved results in that complications are avoided [199–202].”