Severe hypoglycemia in critically ill patients: Risk factors and outcomes*

By J. Krinsley, Aarti Grover. Critical Care Medicine, 2007

680 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism

View Paper: https://www.semanticscholar.org/paper/0745259869bbdd3edbff0392d13f4b65dfcd5a22

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In Endocrinology, Diabetes and Metabolism

1. P. Cryer
2. Djillali Annane
3. J. Krinsley
4. G. Umpierrez
5. John B. Buse
6. V. Basevi

Citations in the corpus

• Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society (2013, background): “The risk factors for inpatient hypoglycemia include older age, presence of comorbidities, diabetes, increasing number of antidiabetic agents, tight glycemic control, septic shock, renal insufficiency, mechanical ventilation, and severity of illness (75,76).”
• A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study (2009, background): “Secondly, associated risks of IIT included hypoglycaemia, implying increases in workload and stress [4], and potential complications [5].”
• Management of hyperglycemia in hospitalized patients in non-critical care setting: an endocrine society clinical practice guideline. (2012, background): “The key predictors of hypoglycemic events in hospitalized patients include older age, greater illness severity (presence of septic shock, mechanical ventilation, renal failure, malignancy, and malnutrition), diabetes, and the use of oral glucose lowering medications and insulin (134, 135).”
• The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study (2010, background): “A case-control study of patients with and without diabetes in an intensive care unit found that hypoglycaemia was an independent risk factor for mortality (relative risk of 2.28).”
• Glycemic variability: A strong independent predictor of mortality in critically ill patients* (2008, background): “Two recent trials were terminated prematurely in part because of excessive rates of severe hypoglycemia (SH) (glucose level 40 mg/dL) (15, 16), recently confirmed to independently confer increased risk of mortality in a heterogeneous population of critically ill patients, on the basis of both multiv”